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Actor Critic with Experience Replay-based automatic treatment planning for prostate cancer intensity modulated radiotherapy
Abrar, Md Mainul, Sapkota, Parvat, Sprouts, Damon, Jia, Xun, Chi, Yujie
Background: Real-time treatment planning in IMRT is challenging due to complex beam interactions. AI has improved automation, but existing models require large, high-quality datasets and lack universal applicability. Deep reinforcement learning (DRL) offers a promising alternative by mimicking human trial-and-error planning. Purpose: Develop a stochastic policy-based DRL agent for automatic treatment planning with efficient training, broad applicability, and robustness against adversarial attacks using Fast Gradient Sign Method (FGSM). Methods: Using the Actor-Critic with Experience Replay (ACER) architecture, the agent tunes treatment planning parameters (TPPs) in inverse planning. Training is based on prostate cancer IMRT cases, using dose-volume histograms (DVHs) as input. The model is trained on a single patient case, validated on two independent cases, and tested on 300+ plans across three datasets. Plan quality is assessed using ProKnow scores, and robustness is tested against adversarial attacks. Results: Despite training on a single case, the model generalizes well. Before ACER-based planning, the mean plan score was 6.20$\pm$1.84; after, 93.09% of cases achieved a perfect score of 9, with a mean of 8.93$\pm$0.27. The agent effectively prioritizes optimal TPP tuning and remains robust against adversarial attacks. Conclusions: The ACER-based DRL agent enables efficient, high-quality treatment planning in prostate cancer IMRT, demonstrating strong generalizability and robustness.
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Clearview AI was built with the help of far-right extremists, reveals a report
A report reveals the controversial face recognition software Clearview AI was developed with help from far-right extremists. The Huffington Post claims founder Hoan Ton-That has close ties with several extremists, attended dinners organized by alt-right groups and had employees famous for hate speech. It includes Charles Johnson, owner of a crowdfunding platform for white supremacists and Jack Posobiec, who led the Pizzagate campaign, along with Peter Thiel and his associate Jeff Giesa who is said to donate to alt-right causes, the Huffington Post claims. The report claims to have videos, messages and emails linking the Clearview founder to these individuals as well as evidence suggesting the technology was designed specifically to'identify every illegal alien in the country.' Ton-That has commented on these allegations in an email to DailyMail.com,
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Omega Medical Imaging First in the World to Receive FDA Clearance on Artificial Intelligence Imaging System that Reduces Dose - Omega Medical Imaging
Omega Medical Imaging, manufactures of Artificial Intelligence Fluoroscopy/Cine (AIF/C) Imaging systems, just announced the Food and Drug Administration 510 (k) clearance of FluoroShield with their 2020 Cardiac Flat Panel Detector. The unique FluoroShield system allows for auto collimation during interventional fluoro or cine cases while maintaining a perspective of surrounding anatomy. The blended image incorporates a lower frequency refresh of the peripheral image area. This combined image (live fluoroscopy or cine of ROI background refreshed at a rate of once or twice per second) increases the quality of information presented during interventional procedures. Brian Fleming, President of Omega Medical Imaging states, "Until now products on the market have only been able to manage radiation to patients and staff. FluoroShield is the only system in the world that provides an actual reduction in dose. The impact of this groundbreaking solution for patients and healthcare providers is substantial. I am very grateful to be a part of a team that pushes the envelope in the development of safer healthcare solutions."
Mars Is Still a Priority Under Trump. Earth, Not So Much.
The president-elect seems to favor a strong human spaceflight program--but monitoring our own planet from space is likely not on his agenda. Trump and his team seem to favor plans to move humans deeper into space and perhaps to Mars. Recently, it seemed as though support for space exploration, both human and robotic, was reaching a crescendo. Last year's Pluto flyby, a new mission to Jupiter, and a planned mission to the icy moon Europa showcased NASA's commitment to exploring deep space, while major announcements from President Obama and Elon Musk made it sound like efforts to send humans to Mars might finally escape the realm of science fiction. All this activity fueled an optimistic view that exploring space may once again be a national priority.
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Applied AI News
Blue Cross/Blue Shield of Virginia AT&T's Merrimack Valley Works The US Army Laboratory Command's (Richmond, VA) has developed an (North Andover, MA) has developed Human Engineering Laboratory expert system to classify, evaluate the Expert Capacity and Material (Aberdeen Proving Ground, MD) has and process medical claims. The system, System (XCAM), an expert system awarded a $2.4 million contract to called MedScreen, reportedly which simplifies forecast evaluations Carnegie Group (Pittsburgh, PA) to can process up to 500 claims in 45 for a manufacturing operation The continue work on a knowledge-based minutes, an operation that used to system automates the analysis of logistics planning system. The system take several days to complete. The IBM (Armonk, NY) and Dragon Systems NRM has been successfully deployed ICL (Birmingham, England) has completed (Newton, MA) have jointly in a number of Australian banks, as a pilot test of an intelligent developed VoiceType, a speech recognition well as a food storage and distribution system for field service diagnosing system based on elements of center. ICL used a laptop-based allows hands-free typing.
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